Fast Facts: Comprehensive Genomic Profiling : Making Precision Medicine Possible / Bernardo L. Rapoport, Giancarlo Troncone, Fernando Schmitt, Simon Nayler [electronic resource]
Basel : S. Karger, 2020Description: 1 online resource (108 pages) : 17 figures, 17 in color, 13 tablesISBN:- 9783318068191
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Cancer is a multifaceted disease in which genetic changes induce uncontrolled tumor growth. Genomic characterization of cancer is now leading to better diagnostic, prognostic and predictive biomarkers, and effective individualized management. 'Fast Facts: Comprehensive Genomic Profiling' provides a crash course in the science, methods and application of genomic profiling. Assuming only the most basic knowledge - or memory - of cell biology, the authors provide an overview of DNA and RNA biology and next-generation sequencing. This sets in context the descriptions of prognostic and predictive biomarkers for different cancer types and genomic-based treatments. Finally, but importantly, some of the practicalities of gaining and interpreting genomic information are described. Whether you need a primer or a refresher, this short colorful book demystifies this complex subject.
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